Bicycle frames are constructed from materials which place emphasis on being strong, lightweight and stiff to aid power transfer. Aluminium, titanium, steel and carbon are widely used in all levels of frame production.
Bicycle wheels come in a wide range of sizes from 12" wheels found on smaller Kids Bikes to larger 29" Mountain Bike and 700c Road Bike wheels. Larger wheels are normally faster and more stable at speed and their larger contact patch improves grip too. Smaller wheels are normally lighter, more manoeuvrable and have quicker acceleration.
Wheel sizes are defined by the country that first popularised the style of bike that used them - so you'll see some imperial and some metric measurements listed. Wiggle includes the ISO standard in brackets after each for ease of comparison.